If you are arriving by YPR-KCG Prasanthi nilayam express at 5:00 am and need to travel to the north west of the city, into areas like Kukatpally, Miyapur etc & to South East areas like NGO's colony, LB Nagar, there are APSRTC has arranged connecting city buses which would start right from the Main entrance of the station, exclusively for the purpose of passengers arriving by this train. Don't depened on autos & taxis as they charge hefty amounts. Use these buses instead.
Other wise you would still have first MMTS going towards Secunderabad & onto Lingampalli at 5:15 am.